Neuroblastoma occurs as a derivative of neural crest cells and occasionally can be matured from a malignant neuroblastoma into a benign ganglioneuroma.
Neuroblastoma is responsible for 10 percent of all pediatric neoplasms and seen most often in the newborn period and the median age at diagnosis is 2 years. It has the highest rate of spontaneous regression of any pediatric tumor. But this tumor
presents with metastases in 70% of cases, and despite aggressive multimodal therapy, has not significantly increased the proportion of patients with advanced disease who are cured. Recently, combined treatment, including aggressive chemotherapy,
radiation therapy, and surgery, has induced complete regression and prolongation of disease free survival in some patients. This article presents a case of complete regression of neuroblastoma with brief review of the literature.
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